M-Series

Standard, Pilot Scale, SIP Bioreactors / Fermentors

Solaris offers the M-series "standard," SIP dished bottom, pilot scale bioreactors and fermentors. There are 6 standard vessel sizes ranging from 30 - 200L total volumes, completely configurable with an extensive range of options and accessories.

Solaris Pilot Plant Fermentors In Use At Major University

The Solaris M-Series Pilot Plant Fermentor / Bioreactor is featured at the University of Sheffield at its Advanced Biomanufacturing Centre. Solaris Fermentors are also featured in the Diamond Pilot Plant Video on their facilities page.

Product Details

Video

Benefits

Solaris M Series - Pilot Scale Bioreactor and Fermentor

Benefits of Solaris M-Series Pilot Scale Bioreactor + Fermentor System:

Compact design
Available Pneumatic cover lift
Re-sterilizable addition system (utilizing steam bridge)
Double jacket (side/bottom), heat exchangers & recirculating pump for most efficient heat transfer & optimal temperature control.
Top or bottom mounted agitation utilizing brushless DC motor with 1 to 2,000 RPM range.
Agitation online absorbed Torques (Nm) and Power (W) available.
Automatic mechanical seal lubrication with steam condensate loop.
Tri-Clamp stainless steel pipe fittings.
19’’ colored touch screen industrial HMI utilizing powerful & intuitive SBC16 controlling software.
Digital online DO, pH, conductivity, &/or ORP sensor management utilizing Hamilton ARC Modbus communication.
Cell density: OD or VCD/permittivity probe integration available.
Other parameters available including weight, CO2, etc.
Peristaltic pump options for feed, pH control, etc.
Up to 5 mass flow controller integration.
Flexible options for data export and management.
Fermentation or cell culture configurations available.

Gas Mixing

Maximum control for mass transfer

Thermal mass flow controllers (MFC) allow precise flow rate control of individual gasses. Up to 5 MFCs can be configured within each unit & integrated to the controlling software. This enables flexible aeration options for a wide range of applications.

Various agitator configurations are key to match to each process. For example, in high oxygen demand fermentation, a Rushton style impeller system may be utilized, whereas in more shear sensitive cell cultivation, a axial style impeller may be better suited.

The powerful software & control platform allows precise cascade adjustment of multiple parameters to manage gas transfer, allowing better maximization of OTR, kLa, etc.

Software

User-friendly Software for Pilot Scale Bioreactor / Fermentor

Solaris controlling software offers a simply laid out, yet powerful platform for experimental design planning and process control. The graphical user interface enables the intuitive selection & adjustment of control functions.

Extracted data is compatible with Window Excel, but in addition, Solaris offers a platform where fermentation data can be easily exported in real time & thus managed. This software is included in supply and can be installed on an unlimited number of the client’s PC or laptops.

Features

Home screen with Multi-level password protection.
Synoptic page also allowing manual operation of components (pumps, valves etc.)
Controller page allows easy access to set points, current values, control modes, PID customization, alarm limits, etc.
SBC-16 manages process phases such as: stand by phase (free use, maintenance); pre-cultivation phase (automatically entered after sterilization, managing the pre-innoculum); and cultivation phase.
Trends page allows real time process variable monitoring, comparison, data export, etc. On the graphical interface, up to 6 process and/or set point variables can be viewed simultaneously. Dynamic zooms and graphical configurations within set time frames can be changed interactively.

Solaris Fermentation Manager

Extracted data is compatible with Windows Excel, however, Solaris has also developed a platform where fermentation data can be easily exported in real time & thus managed in various protocols.

Solaris Logic Parser

The Solaris Logic Parser plug-in, integrated to Leonardo 3.0 as standard, gives users the additional capability of customized control by relating all available process variables with common conditional statements. The communication between Leonardo 3.0 and logical functions is via exchange database.

Applications