Popular Cell Lines
Choosing the right cell line for a new product can be a daunting task. Be it strains, plasmids, recombination methods, or inducible factors: the options are seemingly endless for scientists.
To help relieve the stress of this first step, Solaris Biotech USA presents the “Industry’s Greatest Hits” -- a taxonomic atlas for the most popular cell lines and products used in everyday life.
From xanthan gum to chemotherapy, “Industry’s Greatest Hits” is a working database to reference how the strains you consider are used by other scientists.
Food & Beverage
Acetobacter acetti
Type of Cell:
Bacteria
Product:
Acetic Acid (Vinegar)
Aspergillus niger
Type of Cell:
Fungi
Product:
Citric Acid
Gluconobacter oxydans
Type of Cell:
Bacteria
Product:
Acetic Acid (Vinegar)
Saccharomyces cerevisiae
Type of Cell:
Fungi (yeast)
Product:
Bakers Yeast / Brewers Yeast / Ethanol
Medicine
Acremonium chrysogenum
Type of Cell:
Fungi
Product:
Cephalosporin C (antibiotic), Semisynthetic cephalosporins
Aspergillus nidulans
Type of Cell:
Fungi
Product:
Penicillin
Bacillus brevis
Type of Cell:
Bacteria
Product:
Gramicidin S (antibiotic)
Chinese Hamster Ovary (CHO)
Type of Cell:
Mammalian
Product:
Bevacizumab (Avastatin), Ipilimumab, top selling drugs each year
Escherichia coli
Type of Cell:
Bacteria
Product:
Insulin, Glucosamine (osteoarthritis), Semisynthetic cephalosporins, Artemisinin (malaria drug)
Penicillium chrysogenum
Type of Cell:
Fungi
Product:
Penicillin, Semisynthetic cephalosporins
Penicillium rubens
Type of Cell:
Fungi
Product:
Penicillin
Saccharomyces cerevisiae
Type of Cell:
Fungi (yeast)
Product:
Insulin, hepatitis B surface antigen, urate oxidase, glucagons, GM-CSF, hirudin, PDGF, Artemisinin precursor Artemisinic acid (malaria drug)
Industry
Aspergillus niger
Type of Cell:
Fungi
Product:
Phytase
Bacillus subtilis
Type of Cell:
Bacteria
Product:
Alpha amylase (enzyme)
Escherichia coli
Type of Cell:
Bacteria
Product:
Cellulase, exoglucanase, aspartase, captopril esterase
Pichia (Komagataella) pastoris
Type of Cell:
Fungi (Filamentous)
Product:
tumor necrosis factor, gelatin, intracellular tetanus toxin fragment C, serum albumin. JLA pap
Supplements
Bacillus subtilis
Type of Cell:
Bacteria
Product:
Vitamin B2 (Riboflavin) synthesis Branched chain amino acids, Guanosine Monophosphate (flavoring agent)
Blakeslea trispora
Type of Cell:
Fungi
Product:
beta-carotene (food coloring agent / reduced oxidative stress)
Escherichia coli
Type of Cell:
Bacteria
Product:
L-Threonine, L-Alanine, L-Hydroxyproline, L-Tryptophan, L-Phenylalanine, D-Lactic acid, Succinic acid, Shikimic acid, D-Mannitol (sweetener), Lycopene (Carotenoid - coloring agent)
Gluconobacter oxydans
Type of Cell:
Bacteria
Product:
Vitamin C
Kluyveromyces lactis
Type of Cell:
Fungi
Product:
Lactic acid
Saccharomyces cerevisiae
Type of Cell:
Fungi (yeast)
Product:
L-Lactic acid, D-Lactic acid, Succinic acid, Malic acid
Xanthomonas campestris
Type of Cell:
Fungi (yeast)
Product:
Xanthan gum - food additive
Biofuel
Clostridium acetobutylicum
Type of Cell:
Bacteria
Product:
Acetone, Butanol, Ethanol fermentation
Escherichia coli
Type of Cell:
Bacteria
Product:
Ethanol, 1,3-propanediol (PDO, precursor for synthetic polymers)
Saccharomyces cerevisiae
Type of Cell:
Fungi (yeast)
Product:
Ethanol
Materials
Corynebacterium glutamicum
Type of Cell:
Bacteria
Product:
P(3HB) bioplastics
Escherichia coli
Type of Cell:
Bacteria
Product:
Insulin, Glucosamine (osteoarthritis), Semisynthetic cephalosporins, Artemisinin (malaria drug)
Agriculture
Saccharopolyspora spinosa
Type of Cell:
Bacteria
Product:
Spinosad (insect control agent)
Streptomyces avermitilis
Type of Cell:
Bacteria
Product:
Avermectin (pesticide)
Trichoderma harzianum
Type of Cell:
Fungi
Product:
Fungicide
